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The purpose of this study was to examine the relationship between mental health and social capital among the students of the Medical Sciences Department at Tehran University. This research was a descriptive analytic study which considered 400 whose average age was 23±3. The Bullen’s questionnaire and general health questionnaire were used for collecting the data and logistic regression was utlized to analyze the data. The results of the study showed that 52.25% of the participants were healthy. In addition, the results of hypothesis testing showed that there was not any significant relationship between mental health and social capital. However, there was a significant relationship between the age difference with dimensions of anxiety and sleep disorder. The odds ratio showed that with an increase in age each year, the chance of suffering from anxiety and sleep disorder was also increased by.88. Finally, it appeared that the coming of graduation time and worrying about future professional and educational life might create anxiety and disorders with an increase of age among students of the Medical Sciences Department.